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Steroids weaken the cardiac contractile force and induce cardiac muscle degeneration, which can lead to cardiac arrhythmia and sudden death [31, 32, 33, 34]. The exacerbating effect of anabolic steroids and testosterone on diabetes has been known for a long time. The use of these substances increases insulin resistance and the risk of diabetes and it may induce prediabetes [35]. The sharing of syringes with other users may cause a blood-transmitted disease, such as hepatitis or HIV [36]. The excessive use of testosterone and anabolic steroids also increases the risk of liver damage and cancer [16, 37]. Anabolic steroids that are administered orally are more harmful to the liver than those that are injected. Liver diseases vary from reversible, slight cell damage and jaundice to malignant liver tumours with a bad prognosis even when treated. Adverse effects: mental disorders. Testosterone and anabolic steroids also affect the central nervous system. Their sites of action within the brain are closely connected to the centers that regulate mood, sexuality, and aggressiveness [38]. About 20 to 30 percent of the people who use excessive doses of testosterone and anabolic steroids have obvious mood disorders during the period of use. These disorders meet the criteria of the psychiatric disease classification and they include depression, anxiety, psychotic reactions with hallucinations, hypomania, and weakened level of cognitive performance [8, 25, 31]. It is also estimated that about one-third of anabolic steroid users experience anabolic steroid [39, 40] addiction [39, 40]. About 30 percent of the people who use excessive doses of testosterone and anabolic steroids are aggressive, hostile, and irritated during the intake period. Based on a number of case reports, hormones weaken impulse control [31]. The mood disorders and behavioural changes are likely to be the sum of many factors. The high quantities of anabolic steroids are one explanatory factor, but the user’s personality and psycho-social environment also affect the behaviour caused by anabolic steroid use. For example, there is no strong evidence pointing to the so-called roid rage. Aggressive and violent behaviour has often been linked to other intoxicants in addition to anabolic steroids, as well as to susceptibility to other risk behaviours. However, anabolic steroids may act as the trigger [29, 41, 42, 43, 44]. Timo Seppala Medical Director Finnish Center for Integrity in Sports FINCIS (previously the Finnish Antidoping Agency FINADA) Testosterone. While there are numerous hormones we may aptly label important in-terms of proper function and health, for men the hormone testosterone is of great importance. Both men and women require testosterone for a well-functioning body but men do so in far higher amounts then their female counterparts, top legal steroids. While a very important hormone and largely misunderstood, testosterone is easily one of the most exciting hormones we can discuss, especially as it pertains to performance enhancing; in-fact, we can confidently say it is the most important hormone in the performance enhancing game. Without adequate levels of testosterone our goals will largely not be met and without increased levels you can in many cases wave goodbye to the idea of surpassing these goals to a great degree.
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